University of Minnesota
Office for Technology Commercialization
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Your search resulted in 18 matches

Acute Lymphoblastic Leukemia Cell Line and Mouse Model 20100059
Mouse cell line mimics common form of leukemia. (2012-05-02) (20100059)
Affinity-Based Cell Separation for Cell-Based Therapy and Stem Cell Research 20110207
In the PEG affinity-based cell separation method, cells of interest are captured on a substrate through interactions between a cell surface biomarker and a ligand immobilized on the substrate. Cells can then be detached through the addition of a polyethylene glycol conjugate (PEG) and a heterodimer. The detachment method can be tuned for cells with specific affinity to the substrate using different sized PEGs. The substrate can be washed and reused efficiently by using solutes that competitively bind with the PEG used. (2012-07-26) (20110207)
Avian Cell Lines: A Rapidly Growing Immortal Chicken Embryo Fibroblast Cell Line (WK-1) Z04191
WK-1 is an immortalized chicken embryo fibroblast cell line. (2012-05-02) (Z04191)
Avian Cell Lines: Clonal Variant Cell Line for Improved Vaccine Virus Propagation 20120137
Avian clonal variant cell line improves Marek's Disease vaccine for poultry. (2012-05-02) (20120137)
Avian Cell Lines: Retrovirus Free Cell Line for Vaccine Development 95149
This retrovirus free cell line allows for the production of human and animal vaccines and is useful for developing vaccines which are not susceptible to retrovirus contamination. This is important because it will reduce the side effects of a vaccine developed from this cell line, and reduce the chance of vaccine recall by the FDA. (2012-05-07)(95149)
Canine Cell Lines: Melanoma, Hemangiosarcoma and Osteosarcoma 20110168
Canine cell lines include melanoma, hemangiosarcoma and osteosarcoma cell lines and tissue samples for research. (2012-05-03) (20110168)
CM: Cellulosic Biofuel, Chemical, and Ethanol Production Z02025
The bioreactor creates “designer organisms” that utilize renewable resources to produce cellulosic fuels, cellulosic chemicals, and cellulosic ethanol. Microbe growing bioreactors are vital systems in the development of these organisms that must be able to consume a variety of feedstocks, survive the toxic by-products of the production process, and must withstand a variety of temperatures and conditions. Such robust organisms are a major focus of biofuel companies that are currently investing significant amounts of money into biotechnology research and the development of these organisms. (2012-05-07)(Z02025)
CM: Reverse Plug Cytometer for Cell Tracking Z07102
The Reverse Plug Cytometer combines the positive features of traditional flow cytometers, laser scanning, and imaging cytometers but specifically, enables single cell tracking of large numbers of cells. (2012-05-03) (Z07102)
GFP Displaying Transgenic Mouse for Antigen Receptors 20110048
BAC transgenic mouse that expresses GFP when stimulated through the T or B cell antigen receptor has many applications for basic research on the immune system, infectious disease, autoimmune disease, transplantation, vaccination, and immunotherapy for cancer. (2012-05-03) (20110048)
iMycCα/Bcl-XL double transgenic mouse for Plasma Cell Neoplasms Z02078
A mouse model of human plasma cell neoplasms (PCN) that may be useful to study the mechanism of the Myc/Bcl-XL collaboration and to design new approaches for treatment and prevention of human PCNs. (2012-05-30) (Z02078)
Inducible Synthetic Transcription Activators for Bacteria 20100153
The transcription activator constitutes a molecular device that activates gene expression upon induction via a synthetic protein molecule and its complementary DNA promoter sequence. With this molecular device, scienstists and engineers can deliberately and precisely turn on and off the production of proteins in bacteria. (2012-05-08) (20100153)
Iron Deficiency Mouse Model Z09100
Researchers would use the iron deficiency mouse model to understand the fundamental biology behind iron deficiency's effects on the brain. (2012-05-03) (Z09100)
Shuttle Vector for Rickettsia Species 20120126
Plasmid shuttle vectors allow introduction of any gene or group of genes into rickettsiae for testing their function, or for labeling live rickettsiae that express fluorescent markers encoded on the plasmids to study their behavior in cells and organisms. (2012-05-08) (20120126)
Target for Acaricides and Cattle Tick Vaccines Z00105
This tick cell line includes proteins and genes that are new targets for acaricides and vaccines for the control of the cattle tick Boophilus microplus. (2012-05-08) (Z00105)
Transposon Induction of Glioma Brain Tumors and Cancer Stem Z08158
A mouse model for the study of human brain tumors in a variety of ways, such as generation of "humanized" models for high throughput drug screening and candidate gene validation with exceptional speed and flexibility. (2012-05-30) (Z08158)
Transposon-based System for Cancer Gene Identification in Mice Z04200
Cancer gene discovery using mice and a sleeping beauty transposon to tag and clone cancer genes. (2012-05-31) (Z04200)
Vertebrates: DNA-based Transposon System for the Introduction of Nucleic Acid into the DNA of a Cell 96135
This technology encompasses the Sleeping Beauty (SB) transposon system, which includes the SB transposon and its associated transposase. (2012-05-04) (96135)
Vertebrates: Domain Based Fusion Protein Improves Induced Pluripotent Stem Cells 20100137
A fusion protein that improves production of induced pluripotent stem cells (iPSCs) through a transactivation-domain based strategy. Transduction in the presence of this novel fusion protein increases the rate of de-differentiation, the number of iPSCs generated, and the retention of pluripotency. This innovative approach eliminates the need for feeder cells, simplifying the procedure. In addition to induction of pluripotency, this transactivation domain-based strategy may enable direct transdifferentiation without iPSC transition. (2012-01-16) (20100137)
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